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TROY Antibody

Purified Goat Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NS68
Reactivity Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Calculated MW 46015 Da
Additional Information
Gene ID 55504
Other Names Tumor necrosis factor receptor superfamily member 19, TRADE, Toxicity and JNK inducer, TNFRSF19, TAJ, TROY
Target/Specificity TROY
Format 100 mg (0.2 mg/ml) goat polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsTROY Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TAJ, TROY
Function Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes
Citations (0)

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TROY (also designated TAJ), a member of the TNFR superfamily, exists as several isoforms that vary in functions. Full length TROY contains a cytoplasmic tail, which recruits tumor necrosis factor receptor-associated factor (TRAF) 2. The interaction between TROY and TRAF2 promotes cell survival through the NFκB signaling pathway. One truncated version of TROY, designated TNFRSF19, contains a shortened cytoplasmic tail, which prevents TNFRSF19 from activating the NFκB signal transduction pathway.

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$ 295.00
Cat# ABV11542
(40 western blots)
Availability: 5-7days
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