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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLC gamma 2 Antibody   

PLC gamma 2 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - PLC gamma 2 Antibody ABV11547
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16885
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 147870 Da
Additional Information
Gene ID 5336
Other Names PLC, EC , Phosphoinositide phospholipase C , PLC-gamma-2 , Phospholipase C-gamma-2 , PLC-IV , 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma 2
Target/Specificity PLC gamma 2
Format 100 µg (0.5 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsPLC gamma 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLCG2
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Research Areas
Citations (0)

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PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCδ, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.

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$ 245.00
Cat# ABV11547
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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