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NIF1 Antibody

Purified Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession Q9H4Z2
Other Accession NP_071378.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 144893 Da
Additional Information
Gene ID 63925
Other Names NIF1, NIF-1, Nuclear Receptor Coactivator-Interacting Factor 1, ZNF335, Zinc Finger 335
Target/Specificity NIF1
Formulation 100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA, and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsNIF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF335
Function Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters (PubMed:19131338, PubMed:23178126). Enhances ligand-dependent transcriptional activation by nuclear hormone receptors (PubMed:12215545, PubMed:18180299, PubMed:19131338). Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST (PubMed:23178126). Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation (PubMed:23178126).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

NRC-Interacting Factor 1 (NIF1) interacts with the nuclear receptor transcriptional coactivator NRC and enhances ligand-dependent transcriptional activation by nuclear hormone receptors as well as c-Fos and c-Jun. NIF1 may function to influence chromatin structure.

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Discontinued
Cat# ABV11555-100
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