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RbBP5 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - RbBP5 Antibody ABV11560
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8BX09
Other Accession NP_766105
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 59098 Da
Additional Information
Gene ID 213464
Other Names RbBP5, Retinoblastoma binding protein 5; RBQ3, Retinoblastoma binding protein RBQ3
Target/Specificity RbBP5
Format 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsRbBP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rbbp5
Function As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Retinoblastoma binding protein 5 (RbBP5) belongs to a highly conserved subfamily of WD-repeat proteins and it is also a subunit of a human Set1-like histone methyltransferase (HMT) complex. The encoded RbBP 5protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B

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$ 245.00
Cat# ABV11560
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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