|Calculated MW||11025 Da|
|Other Names||MCP1, MCP-1, MCP 1, monocyte chemoattracctant protein-1, monocyte chemoattracctant protein 1, monocyte chemoattracctant protein|
|Formulation||100 µg (0.5 mg/ml) rabbit anti-human MCP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Precautions||MCP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.|
|Tissue Location||Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
Human macrophage/monocyte chemotactic and activating factor (MCAF), also called human monocyte chemotactic protein-1 (MCP-1), is an 8.6 kDa protein containing 76 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.
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