TPO Antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P40225 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 37823 Da |
Gene ID | 7066 |
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Other Names | thrombopoietin, MPL, MPL ligand, Megakaryocyte growth and development factor, MGDF |
Target/Specificity | TPO |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human TPO polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Background Descriptions | |
Precautions | TPO Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THPO |
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Synonyms | MGDF |
Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo.
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