Lymphotactin Antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | P47993 |
Other Accession | NP_032536 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 12467 Da |
Gene ID | 16963 |
---|---|
Other Names | C motif chemokine 1, Cytokine SCM-1, Small-inducible cytokine C1 |
Target/Specificity | Lymphotactin |
Formulation | 100 µg (0.5 mg/ml) Protein A purified rabbit anti-mouse Lymphotactin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Background Descriptions | |
Precautions | Lymphotactin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Xcl1 |
---|---|
Synonyms | Lptn, Ltn, Scyc1 |
Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
Cellular Location | Secreted. |
Tissue Location | Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
Lymphotactin is the only C chemokine so far identified which has a single cysteine residue near the amino terminus. It has 114 amino acids with a 22 amino acids signal peptide. It is produced in activated CD8+ T cells and NK cells. Lymphotactin attracts both T lymphocytes and NK cells.
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