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PDGF-BB Antibody

Purified Rabbit Polyclonal Antibody

  • WB - PDGF-BB Antibody ABV11602
    Western blot analysis using recombinant human PDGF-BB.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01127
Other Accession NP_148937
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27283 Da
Additional Information
Gene ID 5155
Other Names platelet-derived growth factor subunit B
Target/Specificity PDGF-BB
Format 200 µg (0.5 mg/ml) affinity purified rabbit anti-human PDGF-BB polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsPDGF-BB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PDGF2, SIS
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
Cellular Location Secreted. Note=Released by platelets upon wounding
Tissue Location Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
Research Areas
Citations (0)

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Human Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF is composed of a dimer of two chains termed the A chain and B chain, and thus can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-BB is a 14-18.0 kDa protein containing 109 amino acid residues.

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$ 245.00
$ 89.00
Cat# ABV11602
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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