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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDGF-BB Antibody   

PDGF-BB Antibody

Purified Rabbit Polyclonal Antibody

  • WB - PDGF-BB Antibody ABV11603
    Western blot analysis using recombinat murine PDGF-BB. Lane1: 50ng; lane2: 250ng; lane3: 1ug.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31240
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27382 Da
Additional Information
Gene ID 18591
Other Names platelet-derived growth factor subunit B
Target/Specificity PDGF-BB
Format 100 µg (0.5 mg/ml) affinity purified rabbit anti-murine PDGF-BB polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsPDGF-BB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pdgfb
Synonyms Sis
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
Cellular Location Secreted. Note=Released by platelets upon wounding.
Tissue Location Localized to vascular smooth muscle cells. Also weakly expressed by cortical interstitial cells but absent in tubules. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, an increased expression in interstitial cells and in some tubules observed after day 4
Research Areas
Citations (0)

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Mouse Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF-BB is a 24.4.0 kDa protein containing 109 amino acid residues. The reduced form of PDGF-BB shows ~14-18 kDa on SDS-PAGE.

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$ 245.00
$ 89.00
Cat# ABV11603
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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