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VEGF-C Antibody

Purified Goat Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P49767
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Goat IgG
Calculated MW 46883 Da
Additional Information
Gene ID 7424
Other Names VEGF C, Vascular Endothelial Growth Factor C , Vascular endothelial growth factor-related protein C; VRP
Target/Specificity VEGF-C
Formulation 100 µg (0.5 mg/ml) antigen affinity purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsVEGF-C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VEGFC
Function Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.
Cellular Location Secreted.
Tissue Location Expressed in the spleen (PubMed:9247316, PubMed:8700872). Expressed in the lymph node, thymus, appendix and bone marrow (PubMed:9247316). Expressed in the heart, placenta, skeletal muscle, ovary and small intestine (PubMed:8700872, PubMed:8617204) Expressed in the prostate, testis and colon (PubMed:8700872)
Research Areas
Citations (0)
citation

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Background

Vascular Endothelial Growth Factor-C (VEGF-C) is a 125 amino acid protein that plays an important role in angiogenesis and many other biological processes. Human VEGF-C exhibits about 85% homology with murine VEGF-C.

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Discontinued
Cat# ABV11608-100
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