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BMP-1 Antibody

Purified Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13497
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 111249 Da
Additional Information
Gene ID 649
Other Names Bone morphogenetic protein 1, BMP-1,, Mammalian tolloid protein, mTld, Procollagen C-proteinase, PCP, BMP1, PCOLC
Target/Specificity BMP-1
Format 100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-BMP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsBMP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP1
Synonyms PCOLC
Function Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX.
Cellular Location Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Note=Co- localizes with POSTN in the Golgi.
Tissue Location Ubiquitous.
Citations (0)

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BMP-1 is an extracellular zinc endopeptidase of the Astacin family. Defects in BMP-1 are thought to lead to aberrant collagen processing and connective tissue disorders. Many forms of BMP-1 have been reported, with varying truncation at the carboxyterminal end. The long form of BMP-1 is most similar to the Tolloid-like proteins, which have extra EGF-like and CUB domains.

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$ 235.00
Cat# ABV11611
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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