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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Procathepsin K Antibody   

Procathepsin K Antibody

Purified Rabbit Polyclonal Antibody

  • WB - Procathepsin K Antibody ABV11634
    Western blot with Procathepsin K antibody. Lane1: Recombinat Rat Procathepsin K (10ng); Lane2: Recombinant RatProcathepsin K (50ng).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00786
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37104 Da
Additional Information
Gene ID 25425
Other Names CTSK, CTSO, CTSO3
Target/Specificity Procathepsin K
Format 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Formulation 100 µg or 30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsProcathepsin K Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ctsh
Function Important for the overall degradation of proteins in lysosomes.
Cellular Location Lysosome.
Research Areas
Citations (0)

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Cathepsin K, a member of the papain cysteine proteinase family, is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996). Cathepsin K is produced as an inactive proenzyme (35.4 kDa) that is converted to its mature active form (23.5 kDa) by proteolytic cleavage of its 99-amino-acid propeptide domain. The in-vitro processing of Procathepsin K to mature Cathepsin K is autocatalytic.

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$ 265.00
$ 89.00
Cat# ABV11634
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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