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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FGF-1 Polyclonal Antibody   

FGF-1 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody

  • WB - FGF-1 Polyclonal Antibody ABV11648
    Western blot analysis of anti-FGF1 pAb in mouse muscle lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61148
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype rabbit IgG
Calculated MW 17418 Da
Additional Information
Gene ID 14164
Other Names Fibroblast Growth Factor 1, Heparin-binding growth factor 1, HBGF-1, Acidic fibroblast growth factor, aFGF, Putative heparin-binding growth factor 1, Alpha-endothelial cell growth factor, Endothelial cell growth factor alpha
Target/Specificity FGF-1
Format 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsFGF-1 Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fgf1
Synonyms Fgf-1, Fgfa
Function Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity).
Cellular Location Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59 (By similarity).
Research Areas
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Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

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$ 265.00
$ 89.00
Cat# ABV11648
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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