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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Phospho-Caspase-6 (Ser257) antibody   

Phospho-Caspase-6 (Ser257) antibody

Purified Rabbit Polyclonal Antibody

  • WB - Phospho-Caspase-6 (Ser257) antibody ABV11672
    Western blot analysis of 293 cells using Phospho-Caspase-6(Ser257) Polyclonal antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55212
Other Accession O08738 (Mouse), O35397 (Rat)
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 33310 Da
Additional Information
Gene ID 839
Other Names CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Target/Specificity Caspase-6 (Ser257)
Format 100ug (1mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Handling The antibody solution should be gently mixed before use
Background Descriptions
PrecautionsPhospho-Caspase-6 (Ser257) antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP6
Synonyms MCH2
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Caspases are the central components of the apoptotic response. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspases are divided into two classes: the initiator caspases, which include caspase 2, 8, 9 and 10 and the effector caspases, which include caspases 3, 6 and 7. Effector caspases being activated by initiator caspases leads the proteolytic cleavage of a broad spectrum of cellular targets, which ultimately leads to cell death.

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$ 285.00
Cat# ABV11672
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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