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AKR1B10 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody

  • WB - AKR1B10 Polyclonal Antibody ABV11675
    Western blot analysis of anti-AKR1B10 antibody with (1)Jurkat cell, (2)3T3 cells and R.kidne lysate. Antibody sensitivity is also tested by (4)2ng, (5)50ng, (6)60ng human AKR1B10 recombinant protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60218
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36020 Da
Additional Information
Gene ID 57016
Other Names Aldo-keto reductase family 1 member B10, ARL-1, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase, AKR1B10
Target/Specificity AKR1B10
Format 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsAKR1B10 Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1B10
Synonyms AKR1B11
Function Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Cellular Location Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway
Tissue Location Found in many tissues. Highly expressed in small intestine, colon and adrenal gland
Research Areas
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AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications. It has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer.

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$ 265.00
Cat# ABV11675
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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