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Anti-human CD44 antibody

Purified Mouse Monoclonal Antibody

  • WB - Anti-human CD44 antibody ABV11684
    Detection of CD44 by Western blotting. 1.MM1 lysate(20ug). 2.Purified exosomes from humn plasma healthy donors(20ug).
  • E - Anti-human CD44 antibody ABV11684
    PEP-30: 30ug of purified exosomes from human healthy donor's plasma. MM1-30: 30ug of purified exosomes from MM1 cell supernatant. COLO1-30: 30ug of purified exosomes from COLO1 cell supernatant.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16070
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG2b
Calculated MW 81538 Da
Additional Information
Gene ID 960
Other Names CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4
Target/Specificity CD44 (unconjugated)
Format 1 mg/ml in phosphate buffered saline (PBS) with sodium azide (15 mM), Approx. pH: 7.4.
Handling The antibody solution should be gently mixed before use
Background Descriptions
PrecautionsAnti-human CD44 antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD44
Synonyms LHR, MDU2, MDU3, MIC4
Function Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
Tissue Location Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas Expression is repressed in neuroblastoma cells
Citations (0)

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CD44, known also as HCAM, is a 742 amino acids protein involved in hematopoiesis, lymphocytes activation. CD44 is expressed in multiple isoforms. In particular, CD44 is highly expressed in cancer tissues and tumor-derived exosomes, suggesting a role in tumor progression and metastasis.

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$ 365.00
Cat# ABV11684
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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