|Application ||WB, FC, E|
|Calculated MW||47355 Da|
|Other Names||Flotillin-1, FLOT1|
|Format||0.2 mg/ml in phosphate buffered saline (PBS) with sodium azide (15 mM), Approx. pH 7.4.|
|Handling||The antibody solution should be gently mixed before use|
|Precautions||Anti-human Flotillin antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome Endosome. Note=Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
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Flotillin belongs to the band 7.2/stomatin protein family and appears to be strongly expressed in muscle cells and fibroblasts. Flotillin expression is also correlated with Alzheimer development. Flotillin is highly expressed on exosomes and appears to be involved in exosome release. It is considered a common marker for exosomes analyses.
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