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Anti-human Flotillin antibody

Purified Rabbit Polyclonal Antibody

     
  • E - Anti-human Flotillin antibody ABV11688
    Detection of different exosomes purified from cell culture supernatant or human plasma.
  • FC - Anti-human Flotillin antibody ABV11688
    Purified exosomes from MM1(30ug) stained by anti-Flotilin antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession O75955
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47355 Da
Additional Information
Gene ID 10211
Other Names Flotillin-1, FLOT1
Target/Specificity Flotilin (unconjugated)
Format 0.2 mg/ml in phosphate buffered saline (PBS) with sodium azide (15 mM), Approx. pH 7.4.
Handling The antibody solution should be gently mixed before use
Background Descriptions
PrecautionsAnti-human Flotillin antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FLOT1
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
Cellular Location Cell membrane; Peripheral membrane protein. Endosome. Membrane, caveola {ECO:0000250|UniProtKB:O08917}; Peripheral membrane protein {ECO:0000250|UniProtKB:O08917}. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Membrane-associated protein of caveola (By similarity). {ECO:0000250|UniProtKB:O08917, ECO:0000269|PubMed:17081065}
Citations (0)

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Background

Flotillin belongs to the band 7.2/stomatin protein family and appears to be strongly expressed in muscle cells and fibroblasts. Flotillin expression is also correlated with Alzheimer development. Flotillin is highly expressed on exosomes and appears to be involved in exosome release. It is considered a common marker for exosomes analyses.

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$ 385.00
Cat# ABV11688
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