|Application ||WB, E|
|Calculated MW||25066 Da|
|Positive Control||WB, ELISA|
|Application & Usage||Western Blot: 1:500 – 1:2000, ELISA: 1:20000.|
|Other Names||CD28; T-cell-specific surface glycoprotein CD28; TP44; CD28|
|Formulation||PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||CD28 Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in T-cells and plasma cells, but not in less mature B-cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Involved in T-cell activation, induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.