β2 Microglobulin Monoclonal Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P61769 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | Mouse IgG |
Application & Usage | Western blot: 1-5 µg/ml; ELISA |
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Alias Symbol | B2M |
Other Names | B2M, Beta-2-microglobulin |
Appearance | Colorless liquid |
Formulation | 100 ug (1mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | β2 Microglobulin Monoclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
B2M gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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