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Anti-EGFR (Cetuximab), Chimeric Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | AAI18666 |
| Reactivity | Human |
| Host | Human/Mouse Chimeric |
| Clonality | Monoclonal |
| Isotype | Human IgG1 |
| Application & Usage | Neutralization : 1-20 µg/ml; ELISA: 2 µg/ml |
|---|---|
| Alias Symbol | EGFR |
| Other Names | Erbitux, ErbB1 |
| Appearance | Colourless liquid |
| Formulation | 100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-EGFR (Cetuximab), Chimeric Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody. Epidermal growth factor receptor (EGFR) is a receptor found on both normal and tumor cells that is important for cell growth. Cetuximab is an EGFR inhibitor, used to treat cancer by blocking the activity of EGFR and keep cancer from growing. Cetuximab can form a bridge that trigger an immune response by binding to the EGFR on the tumor cells. It is used for the treatment of EGFR-expressing, metastatic colorectal cancer.
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