|Application & Usage||Neutralization : 1-20 µg/ml; ELISA: 2 µg/ml|
|Other Names||Erbitux, ErbB1|
|Formulation||100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4.|
|Reconstitution & Storage||-20 °C|
|Precautions||Anti-EGFR (Cetuximab), Chimeric Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody. Epidermal growth factor receptor (EGFR) is a receptor found on both normal and tumor cells that is important for cell growth. Cetuximab is an EGFR inhibitor, used to treat cancer by blocking the activity of EGFR and keep cancer from growing. Cetuximab can form a bridge that trigger an immune response by binding to the EGFR on the tumor cells. It is used for the treatment of EGFR-expressing, metastatic colorectal cancer.
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