|Application ||WB, DB|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||29424 Da|
|Positive Control||Dot blot|
|Application & Usage||Western blot: 1-4 µg/ml, Dot blot: 1-4 µg/ml|
|Other Names||Corticotropin-lipotropin, Pro-opiomelanocortin, POMC, ACTH, LPH, MSH, NPP, POC, CLIP, Tetracosactide.|
|Formulation||100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol.|
|Reconstitution & Storage||-20 °C|
|Precautions||ACTH Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||ACTH stimulates the adrenal glands to release cortisol. Beta-endorphin and Met-enkephalin are endogenous opiates.|
|Tissue Location||ACTH and MSH are produced by the pituitary gland|
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Provided below are standard protocols that you may find useful for product applications.
Adrenocorticotropic hormone stimulates the adrenal cortex. More specifically, it stimulates secretion of glucocorticoids such as cortisol, and has little control over secretion of aldosterone, the other major steroid hormone from the adrenal cortex. Stimulates secretion of adrenal corticosteroids and induces growth of adrenal cortex. ACTH also called Tetracosactide directly activates G-proteins. A stimulator of adenylate cyclase and cAMP formation, its molecular weight is 2.9335 kDa.
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