|Isotype||Human IgG1, kappa|
|Calculated MW||21050 Da|
|Other Names||TNFSF4; tumor necrosis factor (TNF) superfamily member 4; OX40 ligand; OX-40L; TAX transcriptionally-activated glycoprotein 1; TXGP1; gp34; CD252|
|Formulation||200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300|
|Reconstitution & Storage||-20 °C|
|Precautions||Anti-OX40L (Oxelumab), Human IgG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand, OX40L provides co-stimulatory signal to effector T-cells without CD28 activation.
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