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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Phospho-MYPT1 (Thr696) Antibody   

Phospho-MYPT1 (Thr696) Antibody

Rabbit Polyclonal Antibody

     
  • IHC - Phospho-MYPT1 (Thr696) Antibody ABV11845-100
    Immunohistochemical analysis of MYPT1(pT696) staining in H.breast cancer formalin fixed paraffin embedded tissue section.
  • IF - Phospho-MYPT1 (Thr696) Antibody ABV11845-100
    Immunofluorescent analysis of MYPT1 (pT696) staining in HEK293T cells.
  • WB - Phospho-MYPT1 (Thr696) Antibody ABV11845-100
    Western blot analysis of MYPT1 treated (A); HEK293T UV-treated (B) whole cell lysates.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, ICC
Primary Accession O14974
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 115281 Da
Additional Information
Gene ID 4659
Positive Control WB: HEK293 cell lysates; IHC: human breast cancer tissue; IFC: HEK293 cells
Application & Usage WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100
Alias Symbol PPP1R12A
Other Names MBS, MYPT1, Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit, Myosin phosphatase
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPhospho-MYPT1 (Thr696) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R12A
Synonyms MBS, MYPT1
Function Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.
Cellular Location Cytoplasm. Note=Along actomyosin filaments and stress fibers
Tissue Location Expressed in striated muscles, specifically in type 2a fibers (at protein level).
Research Areas
Citations (0)

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Background

Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

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$ 325.00
Cat# ABV11845-100
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