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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-TP53INP2 Antibody   

Anti-TP53INP2 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - Anti-TP53INP2 Antibody ABV11863-100
    Immunohistochemical analysis of TP53INP2 staining in H.breast cancer formalin fixed paraffin embedded tissue section.
  • IF - Anti-TP53INP2 Antibody ABV11863-100
    Immunofluorescent analysis of TP53INP2 staining in Hela cells.
  • WB - Anti-TP53INP2 Antibody ABV11863-100
    Western blot analysis of TP53INP2 expression in Hela(A); RAW264.7(B); H9C2(C)whole cell lysates.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, ICC
Primary Accession Q8IXH6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23980 Da
Additional Information
Gene ID 58476
Positive Control WB: HeLa, RAW264.7, H9C2 cell lysate; IHC: human breast cancer tissue: IFC: Hela cells
Application & Usage WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100
Alias Symbol TP53INP2
Other Names C20orf110; DOR; PINH; Tumor protein p53-inducible nuclear protein 2; Diabetes and obesity-regulated gene; p53-inducible protein U; PIG-U
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-TP53INP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TP53INP2
Synonyms C20orf110, DOR, PINH
Function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Cellular Location Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation
Research Areas
Citations (0)

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Background

Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

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$ 295.00
Cat# ABV11863-100
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