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Anti-ZNT2 Antibody

     
  • IHC - Anti-ZNT2 Antibody ABV11926-100
    Immunohistochemical analysis of ZNT2 staining in human lung cancer formalin fixed paraffin embedded tissue section.
    detail
  • WB - Anti-ZNT2 Antibody ABV11926-100
    WB analysis of ZNT2 expression in HeLa (A); RAW264.7 (B); PC12 (C) whole cell lysates.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IH
Primary Accession Q9BRI3
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype Rabbit IgG
Calculated MW 40564 Da
Additional Information
Gene ID 7780
Positive Control WB: HeLa, RAW264.7, PC12 cell lystae; IHC: human lung cancer
Application & Usage WB; 1:500 – 1:2000, IHC; 1:50 – 1:200
Other Names ZNT2, Zinc transporter 2, ZnT-2, Solute carrier family 30 member 2
Target/Specificity SLC30A2
Antibody Form Liquid
Appearance Colorless liquid
Handling The antibody solution should be gently mixed before use
Reconstitution & Storage -20°C
Background Descriptions
PrecautionsAnti-ZNT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC30A2 (HGNC:11013)
Function [Isoform 1]: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity (PubMed:21289295, PubMed:25808614, PubMed:25657003, PubMed:30893306, PubMed:17065149, PubMed:22733820). Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells (PubMed:19496757). By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution (PubMed:25808614).
Cellular Location [Isoform 1]: Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Zymogen granule membrane {ECO:0000250|UniProtKB:Q2HJ10}; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein. Note=Localization to lysosomes is induced by TNF-alpha
Research Areas
Citations (0)
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Discontinued
Cat# ABV11926-100
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