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Anti-VPS54 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9P1Q0 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Calculated MW | 110589 Da |
| Gene ID | 51542 |
|---|---|
| Positive Control | WB: Jurkat, rat blood lysate; IHC: human breast cancer tissue |
| Application & Usage | WB; 1:500 – 1:2000, IHC; 1:50 – 1:200 |
| Other Names | HCC8, Vacuolar protein sorting-associated protein 54, Hepatocellular carcinoma protein 8, Tumor antigen HOM-HCC-8, Tumor antigen SLP-8p |
| Target/Specificity | VPS54 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Handling | The antibody solution should be gently mixed before use |
| Reconstitution & Storage | -20°C |
| Background Descriptions | |
| Precautions | Anti-VPS54 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | VPS54 |
|---|---|
| Synonyms | HCC8 |
| Function | Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling (PubMed:25799061). |
| Cellular Location | Golgi apparatus, trans-Golgi network. Membrane {ECO:0000250|UniProtKB:Q9JMK8}. Note=Associates with membranes in an EIPR1-independent manner. {ECO:0000250|UniProtKB:Q9JMK8} |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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