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Anti-ADNP Antibody

     
  • WB - Anti-ADNP Antibody ABV11957-100
    WB analysis of ADNP expression in LOVO (A): HCT11G (B); mouse liver (C): rat fiver (D) whole cell lysates
    detail
  • IHC - Anti-ADNP Antibody ABV11957-100
    Immunohistochemical analysis of ADNP staining in human brain formalin fixed paraffin embedded tissue section.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IH
Primary Accession Q9H2P0
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype Rabbit IgG
Calculated MW 123563 Da
Additional Information
Gene ID 23394
Positive Control WB: LOVO, HCT116, mouse liver, rat liver lysate; IHC: human brain tissue
Application & Usage WB; 1:500 – 1:2000, IH; 1:50 – 1:200
Other Names ADNP1, KIAA0784, Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein
Target/Specificity ADNP
Antibody Form Liquid
Appearance Colorless liquid
Handling The antibody solution should be gently mixed before use
Reconstitution & Storage -20°C
Background Descriptions
PrecautionsAnti-ADNP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADNP
Synonyms ADNP1, KIAA0784
Function May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta- catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. Chromosome {ECO:0000250|UniProtKB:Q9Z103}
Tissue Location Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues
Research Areas
Citations (0)
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Discontinued
Cat# ABV11957-100
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