Anti-ADNP Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IH |
---|---|
Primary Accession | Q9H2P0 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Isotype | Rabbit IgG |
Calculated MW | 123563 Da |
Gene ID | 23394 |
---|---|
Positive Control | WB: LOVO, HCT116, mouse liver, rat liver lysate; IHC: human brain tissue |
Application & Usage | WB; 1:500 – 1:2000, IH; 1:50 – 1:200 |
Other Names | ADNP1, KIAA0784, Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein |
Target/Specificity | ADNP |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Handling | The antibody solution should be gently mixed before use |
Reconstitution & Storage | -20°C |
Background Descriptions | |
Precautions | Anti-ADNP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADNP |
---|---|
Synonyms | ADNP1, KIAA0784 |
Function | May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta- catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. Chromosome {ECO:0000250|UniProtKB:Q9Z103} |
Tissue Location | Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues |
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