|Application ||WB, FC|
|Calculated MW||47518 Da|
|Positive Control||WB: Hela, HepG2, HL-60, Ramos, mouse brain cell line; FC: Ramos cell line|
|Application & Usage||FC: 1:1000; WB: 1:10 – 1:50|
|Other Names||Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A, GOT2|
|Handling||The antibody solution should be gently mixed before use|
|Reconstitution & Storage||-20°C|
|Precautions||Anti-GOT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.|
|Cellular Location||Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane|
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