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Anti-Eg5 Antibody (4H3-1F12)
Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IP |
|---|---|
| Primary Accession | P52732 |
| Reactivity | Human |
| Host | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 4H3-1F12 |
| Calculated MW | 119159 Da |
| Gene ID | 3832 |
|---|---|
| Application & Usage | WB: MCSF, 293T, Jurkat, HeLa cell lysates; IP: Jurkat cells; IF: HeLa cells |
| Other Names | EG5, HKSP, KNSL1, TRIP5 |
| Target/Specificity | KIF11 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-Eg5 Antibody (4H3-1F12) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KIF11 |
|---|---|
| Synonyms | EG5, KNSL1, TRIP5 |
| Function | Motor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis (PubMed:19001501, PubMed:37728657). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle pole |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Eg5 gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
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