Anti-TXNRD2 Antibody (3F2-E12-F10)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9NNW7 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 3F2-E12-F10 |
Calculated MW | 56507 Da |
Gene ID | 10587 |
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Application & Usage | WB: A431, U251, U2OS, Lncap and Hela cell lysates |
Other Names | Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, KIAA1652, TRXR2 |
Target/Specificity | TXNRD2 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | In PBS (pH 7.4) containing with 0.02% NaN3 & 50% glycerol |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Anti-TXNRD2 Antibody (3F2-E12-F10) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TXNRD2 (HGNC:18155) |
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Synonyms | KIAA1652, TRXR2 |
Function | Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690). Maintains thioredoxin in a reduced state. May play a role in redox- regulated cell signaling. |
Cellular Location | Mitochondrion. |
Tissue Location | Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling
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