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Anti-TXNRD2 Antibody (3F2-E12-F10)

Mouse Monoclonal Antibody

     
  • WB - Anti-TXNRD2 Antibody (3F2-E12-F10) ABV12055-100
    Western blot detection of TXNRD2 in A431, U251, U20S, Lncap and Hela cell lysates and using TXNRD2 mouse mAb
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NNW7
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1
Clone Names 3F2-E12-F10
Calculated MW 56507 Da
Additional Information
Gene ID 10587
Application & Usage WB: A431, U251, U2OS, Lncap and Hela cell lysates
Other Names Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, KIAA1652, TRXR2
Target/Specificity TXNRD2
Antibody Form Liquid
Appearance Colorless liquid
Formulation In PBS (pH 7.4) containing with 0.02% NaN3 & 50% glycerol
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-TXNRD2 Antibody (3F2-E12-F10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TXNRD2 (HGNC:18155)
Synonyms KIAA1652, TRXR2
Function Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690). Maintains thioredoxin in a reduced state. May play a role in redox- regulated cell signaling.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690).
Research Areas
Citations (0)
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Background

Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling

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Discontinued
Cat# ABV12055-100
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