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>   home   >   Products   >   Primary Antibodies   >   Anti-MART-1/Melan-A Antibody   

Anti-MART-1/Melan-A Antibody

Rabbit Polyclonal Antibody

     
  • WB - Anti-MART-1/Melan-A Antibody ABV12075-30
    Western blot analysis of MART-1 antibody in: Lane 1: Rec. mouse MART-1 2 ng Lane 2: Rec. mouse MART-1 10 ng Lane 3: Rec. mouse MART-1 50 ng
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q2TA50
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Additional Information
Positive Control WB: Recombinant protein
Application & Usage WB: 1-4 µg
Other Names Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A
Target/Specificity Melan-A
Antibody Form Liquid
Appearance Colorless liquid
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-MART-1/Melan-A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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Background

MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

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$ 89.00
$ 225.00
Cat# ABV12075-30
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