|Isotype||Mouse IgG1, κ|
|Calculated MW||76795 Da|
|Application & Usage||ELISA Capture: 1-10 µg/ml, ELISA Detection: 0.05-0.2 µg/ml|
|Other Names||CEA, Meconium antigen 100, CD_antigen: CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5|
|Reconstitution & Storage||-20 °C|
|Precautions||Anti-CEA Antibody (3C5C10) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon|
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Provided below are standard protocols that you may find useful for product applications.
Carcinoembryonic antigen (CEA) is a complex glycoprotein of molecular weight 200 kDa. In healthy adults, less than 5 ng/ml of CEA is found in the serum. Elevation of CEA antigen is found in the blood of patients with cancer of the lung, liver, pancreas, breast, cervix, prostate and so on. CEA measurement is mainly used as a tumor marker to identify recurrences after surgical resection, or localize cancer spread though dosage of biological fluids. The CEA blood test is not reliable for diagnosing cancer. CEA levels may also be raised in some conditions like ulcerative colitis, pancreatitis and cirrhosis. CEA Antibody is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with native human CEA protein
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