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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-C-Peptide Antibody (4C2F10)   

Anti-C-Peptide Antibody (4C2F10)

Mouse Monoclonal Antibody

     
  • E - Anti-C-Peptide Antibody (4C2F10) ABV12092-500
    Antibody pairs analysis of C-peptide monoclonal antibodies by Sandwich ELISA
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession P01308
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1, κ
Clone Names 4C2F10
Calculated MW 11981 Da
Additional Information
Gene ID 3630
Positive Control ELISA
Target/Specificity C-peptide
Antibody Form Liquid
Appearance Colorless liquid
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-C-Peptide Antibody (4C2F10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INS
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

C-peptide serves as an important linker between A-chain and B-chain of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. The sole interest in C-peptide was as a marker of insulin secretion. Newly diagnosed diabetes patients often get their C-peptide levels measured as a means of distinguishing type 1 and type 2 diabetes. C-peptide is also used for determining the possibility of gastrinomas associated with Multiple Endocrine Neoplasm syndromes (MEN 1). C-Peptide Antibody is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human C-peptide conjugated to KLH.

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$ 265.00
Cat# ABV12092-500
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