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Anti-Alanine Racemase Antibody

Rabbit Polyclonal Antibody

     
  • WB - Anti-Alanine Racemase Antibody ABV12111-30
    Western blot analysis of Alanine Racemase antibody in: Lane 1: Alanine Racemase 2 ng Lane 2: Alanine Racemase 10 ng Lane 3: Alanine Racemase 50 ng
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P10724
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 43593 Da
Additional Information
Positive Control Western blot
Application & Usage Western blot: 1-4 µg
Other Names Alanine Racemase Y354N, alr, dal
Target/Specificity Alanine Racemase
Antibody Form Liquid
Appearance Colorless liquid
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-Alanine Racemase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name alr
Synonyms dal
Function Catalyzes the interconversion of L-alanine and D- alanine. Also weakly active on serine.
Citations (0)

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Background

Mutant Alanine Racemase (Y354N) (mAR-Y354N), a pyridoxal 5- phosphate (PLP) dependent enzyme catalyzes the interconversion of the L-Serine to D-Serine. In WT Alanine Racemase Tyr354 plays a crucial role in defining the strict specificity of AR for alanine, in converting L-Alanine to D-Alanine, which is an important component of the peptidoglycan layer of bacterial cell wall. By mutating the active site Tyr 354 to Asn, the specificity of the enzyme changes and it becomes a racemase with dual specificity for L- Alanine and L-Serine.

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$ 89.00
$ 265.00
Cat# ABV12111-30
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