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Rsf1 monoclonal antibody

Purified Mouse Monoclonal Antibody

     
  • WB - Rsf1 monoclonal antibody ADN10014
    Western blot was performed on nuclear extracts from HeLa cells (HeLa NE, 20 µg) using the monoclonal antibody directed against hRSF1, diluted 1:500 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the left, the position of the protein of interest is shown on the right
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, IP
Primary Accession Q96T23
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 163821 Da
Additional Information
Gene ID 51773
Other Names Remodeling and spacing factor 1, Rsf-1, HBV pX-associated protein 8, Hepatitis B virus X-associated protein, p325 subunit of RSF chromatin-remodeling complex, RSF1, HBXAP, XAP8
Target/Specificity Rsf1
PrecautionsRsf1 monoclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RSF1
Function Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex (PubMed:12972596). Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain (PubMed:11944984, PubMed:11788598).
Cellular Location Nucleus
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.

References

Shamay M.,et al.Genomics 79:523-529(2002).
Shamay M.,et al.J. Biol. Chem. 277:9982-9988(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mao Y.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 290.00
Cat# ADN10014
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