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H2AK5ac polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • CHIP - H2AK5ac polyclonal antibody ADN10132
    ChIP results obtained with the antibody directed against H2AK5ac
  • E - H2AK5ac polyclonal antibody ADN10132
    Determination of the antibody titer
  • DB - H2AK5ac polyclonal antibody ADN10132
    Cross reactivity tests using the antibody directed against H2AK5ac
  • WB - H2AK5ac polyclonal antibody ADN10132
    Western blot analysis using the antibody directed against H2AK5ac
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E, DB
Primary Accession Q7L7L0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 14121 Da
Additional Information
Gene ID 92815
Other Names Histone H2A type 3, HIST3H2A
Target/Specificity H2AK5ac
PrecautionsH2AK5ac polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HIST3H2A
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

References

Marzluff W.F.,et al.Genomics 80:487-498(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Aihara H.,et al.Genes Dev. 18:877-888(2004).

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$ 290.00
Cat# ADN10132
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