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SAP30 polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • WB - SAP30 polyclonal antibody ADN10150
    Western blot analysis using the antibody directed against SAP30
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O75446
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 23306 Da
Additional Information
Gene ID 8819
Other Names Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30, SAP30 (HGNC:10532)
Target/Specificity SAP30
PrecautionsSAP30 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAP30 (HGNC:10532)
Function Involved in the functional recruitment of the Sin3- histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N- CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones.
Cellular Location Nucleus.
Tissue Location Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus; lowest levels in brain, placenta, lung and kidney.
Citations (0)

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Background

Involved in the functional recruitment of the Sin3- histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N- CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones.

References

Zhang Y.,et al.Mol. Cell 1:1021-1031(1998).
Laherty C.D.,et al.Mol. Cell 2:33-42(1998).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wysocka J.,et al.Genes Dev. 17:896-911(2003).
Olsen J.V.,et al.Cell 127:635-648(2006).

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$ 190.00
Cat# ADN10150
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