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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Med26 polyclonal antibody   

Med26 polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • WB - Med26 polyclonal antibody ADN10161
    Western blot analysis using the antibody directed against Med26 
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O95402
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 65446 Da
Additional Information
Gene ID 9441
Other Names Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70 kDa component, ARC70, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26, Transcriptional coactivator CRSP70, MED26, ARC70, CRSP7
Target/Specificity Med26
PrecautionsMed26 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED26
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

References

Ryu S.,et al.Nature 397:446-450(1999).
Naeaer A.M.,et al.Nature 398:828-832(1999).
Sato S.,et al.Mol. Cell 14:685-691(2004).
Zhang X.,et al.Mol. Cell 19:89-100(2005).

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$ 190.00
Cat# ADN10161
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