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MBD4 polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • E - MBD4 polyclonal antibody ADN10165
    Determination of the titer
  • WB - MBD4 polyclonal antibody ADN10165
    Western blot analysis using the antibody directed against MBD4
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O95243
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 66051 Da
Additional Information
Gene ID 8930
Other Names Methyl-CpG-binding domain protein 4, 3.2.2.-, Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein MBD4, Mismatch-specific DNA N-glycosylase, MBD4, MED1
Target/Specificity MBD4
PrecautionsMBD4 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MBD4
Function Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
Cellular Location Nucleus.
Citations (0)

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Background

Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.

References

Hendrich B.,et al.Mol. Cell. Biol. 18:6538-6547(1998).
Hendrich B.,et al.Mamm. Genome 10:906-912(1999).
Bellacosa A.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:3969-3974(1999).
Owen R.M.,et al.Oncol. Rep. 17:111-116(2007).
Guo J.H.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.

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$ 190.00
Cat# ADN10165
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