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Mll4 polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • E - Mll4 polyclonal antibody ADN10173
    Determination of the titer 
  • WB - Mll4 polyclonal antibody ADN10173
    Western blot analysis using the antibody directed against Mll4 (1)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O14686
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 593389 Da
Additional Information
Gene ID 8085
Other Names Histone-lysine N-methyltransferase 2D, Lysine N-methyltransferase 2D, 2.1.1.43, ALL1-related protein, Myeloid/lymphoid or mixed-lineage leukemia protein 2, KMT2D, ALR, MLL2, MLL4
Target/Specificity Mll4
PrecautionsMll4 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KMT2D
Function Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
Cellular Location Nucleus.
Tissue Location Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver
Citations (0)

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Background

Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.

References

Prasad R.,et al.Oncogene 15:549-560(1997).
Scherer S.E.,et al.Nature 440:346-351(2006).
Goo Y.-H.,et al.Mol. Cell. Biol. 23:140-149(2003).
Olsen J.V.,et al.Cell 127:635-648(2006).
Mo R.,et al.J. Biol. Chem. 281:15714-15720(2006).

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$ 190.00
Cat# ADN10173
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