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>   home   >   Products   >   Primary Antibodies   >   ZBTB38 polyclonal antibody   

ZBTB38 polyclonal antibody

Purified Rabbit Polyclonal Antibody

  • E - ZBTB38 polyclonal antibody ADN10191
    Determination of the titer
  • WB - ZBTB38 polyclonal antibody ADN10191
    Western blot analysis using the antibody directed against ZBTB38
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NAP3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 134257 Da
Additional Information
Gene ID 253461
Other Names Zinc finger and BTB domain-containing protein 38, ZBTB38 (HGNC:26636)
Target/Specificity ZBTB38
PrecautionsZBTB38 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB38 (HGNC:26636)
Function Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl- CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA- replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters.
Citations (0)

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Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).


Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Olsen J.V.,et al.Cell 127:635-648(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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$ 190.00
Cat# ADN10191
(40 western blots)
Availability: 2-3 days
Bulk Size
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