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PAPD4 polyclonal antibody

Purified Rabbit Polyclonal Antibody

     
  • E - PAPD4 polyclonal antibody ADN10194
    Determination of the titer
  • WB - PAPD4 polyclonal antibody ADN10194
    Western blot analysis using the antibody directed against PAPD4
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6PIY7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 56028 Da
Additional Information
Gene ID 167153
Other Names Poly(A) RNA polymerase GLD2, hGLD-2, 2.7.7.19, PAP-associated domain-containing protein 4, Terminal uridylyltransferase 2, TUTase 2, PAPD4, GLD2
Target/Specificity PAPD4
PrecautionsPAPD4 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAPD4
Function Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla
Citations (0)

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Background

Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Kwak J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:4407-4412(2004).
Rouhana L.,et al.RNA 11:1117-1130(2005).
Mullen T.E.,et al.Genes Dev. 22:50-65(2008).

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$ 195.00
Cat# ADN10194
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