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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GATA1 Antibody (S142)   

GATA1 Antibody (S142)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GATA1  Antibody (S142) AE1013a
    Western blot analysis of extracts from K562 cells using GATA1 Antibody (S142) (#AE1013a).
  • IHC - GATA1  Antibody (S142) AE1013a
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GATA1 Antibody (S142) (#AE1013a).
  • IF - GATA1  Antibody (S142) AE1013a
    Immunofluorescence staining of methanol-fixed HeLa cells using GATA1 Antibody (S142) (#AE1013a,Red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15976
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Concentration 1mg/ml
Isotype Rabbit IgG
Calculated MW 42751 Da
Additional Information
Gene ID 2623
Other Names Erythroid transcription factor, Eryf1, GATA-binding factor 1, GATA-1, GF-1, NF-E1 DNA-binding protein, GATA1, ERYF1, GF1
Target/Specificity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution WB~~1:500~1:1000
Format affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGATA1 Antibody (S142) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA1
Synonyms ERYF1, GF1
Function Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
Cellular Location Nucleus.
Tissue Location Erythrocytes..
Research Areas
Citations (0)

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This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.


Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis. Klusmann JH, et al. Genes Dev, 2010 Aug 1. PMID 20679399.
HSP27 controls GATA-1 protein level during erythroid cell differentiation. de Thonel A, et al. Blood, 2010 Jul 8. PMID 20410505.
Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation. Wierenga AT, et al. Blood, 2010 Jun 3. PMID 20339093.
Human promoter mutations unveil Oct-1 and GATA-1 opposite action on Gfi1b regulation. Hern谩ndez A, et al. Ann Hematol, 2010 Aug. PMID 20143233.
The transcription factor GATA-1 is overexpressed in breast carcinomas and contributes to survivin upregulation via a promoter polymorphism. Boidot R, et al. Oncogene, 2010 Apr 29. PMID 20101202.

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$ 325.00
Cat# AE1013a
(40 western blots)
Availability: 7-10 days
Bulk Size
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