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ABCB5 AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1007a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ABCB5 Antibody - Product info | |
| Other Accession | NP_848654 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
ABCB5 Antibody - Additional info | |
| Other Names ATP-binding cassette, sub-family B (MDR/TAP), member 5 ; ABCB5alpha; ABCB5beta; EST422562; ATP-binding cassette, sub-family B, member 5N: P-glycoprotein ABCB5 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCB5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCB5 Antibody - Application data
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AF1007a (0.03 µg/ml) staining of A431 cell lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
ABCB5 Antibody - Related products
AP6122a: ABCB5 Antibody (N-term)
RI10015: ABCB5 predesign siRNA
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).
REFERENCES
ABCB5 gene amplification in human leukemia cells. Frank NY, et al. Leuk Res, 2009 Oct. PMID 19477512. Identification of cells initiating human melanomas. Schatton T, et al. Nature, 2008 Jan 17. PMID 18202660. The Role of heat shock protein 27 in extravillous trophoblast differentiation. Matalon ST, et al. J Cell Biochem, 2008 Feb 15. PMID 17661346. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Frank NY, et al. Cancer Res, 2005 May 15. PMID 15899824. Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes. Chen KG, et al. Pigment Cell Res, 2005 Apr. PMID 15760339.
