|Application ||WB, E|
|Other Accession||NP_001098, 97, 66204 (mouse)|
|Calculated MW||11261 Da|
|Other Names||Acylphosphatase-1, 22.214.171.124, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1, ACYP1, ACYPE|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-ACYP1 (isoform a) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Its physiological role is not yet clear.|
|Tissue Location||Organ-common type isozyme is found in many different tissues|
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Provided below are standard protocols that you may find useful for product applications.
Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
ACYP1 gene possesses two alternative splicing forms that induce apoptosis. Degl'Innocenti D, et al. IUBMB Life, 2004 Jan. PMID 14992377.
The DNA sequence and analysis of human chromosome 14. Heilig R, et al. Nature, 2003 Feb 6. PMID 12508121.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase. Paoli P, et al. J Biol Chem, 2003 Jan 3. PMID 12409302.
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