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Goat Anti-ADRB2R / ADRB2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-ADRB2R / ADRB2 Antibody AF1033a
    AF1033a (0.2 µg/ml) staining of human liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07550
Other Accession NP_000015, 154
Reactivity Human, Cow
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 46459 Da
Additional Information
Gene ID 154
Other Names Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ADRB2R / ADRB2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADRB2
Synonyms ADRB2R, B2AR
Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Cellular Location Cell membrane; Multi-pass membrane protein Note=Colocalizes with VHL at the cell membrane
Research Areas
Citations (0)

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This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.


The Arg16Gly-尾(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure. Leineweber K, et al. Naunyn Schmiedebergs Arch Pharmacol, 2010 Oct. PMID 20803192.
A46G and C79G polymorphisms in the beta2-adrenergic receptor gene (ADRB2) and essential hypertension risk: a meta-analysis. Lou Y, et al. Hypertens Res, 2010 Aug 26. PMID 20739939.
The Gln27Glu polymorphism in 尾2-adrenergic receptor gene is linked to hypertriglyceridemia, hyperinsulinemia and hyperleptinemia in Saudis. Daghestani MH, et al. Lipids Health Dis, 2010 Aug 25. PMID 20738880.
ADRB2 gene variants, dual-energy x-ray absorptiometry body composition, and hypertension in Tobago men of African descent. Beason TS, et al. Metabolism, 2010 Aug 18. PMID 20727557.
Association between Genetic Polymorphisms of Adrenergic Receptor and Diurnal Intraocular Pressure in Japanese Normal-Tension Glaucoma. Gao Y, et al. Ophthalmology, 2010 Aug 10. PMID 20705341.

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$ 325.00
Cat# AF1033a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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