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Goat Anti-AID Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-AID Antibody AF1038a
    AF1038a (0.1 µg/ml) staining of Human Tonsil lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9GZX7
Other Accession NP_065712, 57379
Reactivity Human
Predicted Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 23954 Da
Additional Information
Gene ID 57379
Other Names Single-stranded DNA cytosine deaminase,, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA, AID
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-AID Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AID
Function Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Cellular Location Nucleus. Cytoplasm. Note=Predominantly cytoplasmic but shuttles between the nucleus and the cytoplasm
Tissue Location Strongly expressed in lymph nodes and tonsils.
Research Areas
Citations (0)

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This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).


GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. Maeda K, et al. J Biol Chem, 2010 Jul 30. PMID 20507984.
TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis. Igarashi H, et al. Clin Exp Immunol, 2010 Jul 1. PMID 20491788.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
No association between AICDA 7888 C/T polymorphism, Helicobacter pylori seropositivity, and the risk of atrophic gastritis and gastric cancer in Japanese. Hishida A, et al. Gastric Cancer, 2010 Mar. PMID 20373075.
Determinants of sequence-specificity within human AID and APOBEC3G. Carpenter MA, et al. DNA Repair (Amst), 2010 May 4. PMID 20338830.

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$ 325.00
Cat# AF1038a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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