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Goat Anti-ANKK1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-ANKK1 Antibody AF1063a
    AF1063a (0.1 µg/ml) staining of Human Substantia Nigra lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NFD2
Other Accession NP_848605, 255239
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 84632 Da
Additional Information
Gene ID 255239
Other Names Ankyrin repeat and protein kinase domain-containing protein 1,, Protein kinase PKK2, Sugen kinase 288, SgK288, X-kinase, ANKK1, PKK2, SGK288
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ANKK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANKK1
Synonyms PKK2, SGK288
Tissue Location Highly expressed in brain and weakly expressed in placenta and spinal cord.
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.


Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance. Montag C, et al. Neuropsychopharmacology, 2010 Aug. PMID 20410875.
[DRD2/ANKK1 Taq IA polymorphism and early infant temperament] Ma J, et al. Zhongguo Dang Dai Er Ke Za Zhi, 2010 Feb. PMID 20199723.
CLOCK is suggested to associate with comorbid alcohol use and depressive disorders. Sj枚holm LK, et al. J Circadian Rhythms, 2010 Jan 21. PMID 20180986.
A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes. Dubertret C, et al. Prog Neuropsychopharmacol Biol Psychiatry, 2010 Apr 16. PMID 20138949.
Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. David SP, et al. Nicotine Tob Res, 2010 Mar. PMID 20133381.

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$ 325.00
Cat# AF1063a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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