Goat Anti-ANKK1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8NFD2 |
Other Accession | NP_848605, 255239 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 84632 Da |
Gene ID | 255239 |
---|---|
Other Names | Ankyrin repeat and protein kinase domain-containing protein 1, 2.7.11.1, Protein kinase PKK2, Sugen kinase 288, SgK288, X-kinase, ANKK1, PKK2, SGK288 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-ANKK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ANKK1 |
---|---|
Synonyms | PKK2, SGK288 |
Tissue Location | Highly expressed in brain and weakly expressed in placenta and spinal cord. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
References
Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance. Montag C, et al. Neuropsychopharmacology, 2010 Aug. PMID 20410875.
[DRD2/ANKK1 Taq IA polymorphism and early infant temperament] Ma J, et al. Zhongguo Dang Dai Er Ke Za Zhi, 2010 Feb. PMID 20199723.
CLOCK is suggested to associate with comorbid alcohol use and depressive disorders. Sj枚holm LK, et al. J Circadian Rhythms, 2010 Jan 21. PMID 20180986.
A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes. Dubertret C, et al. Prog Neuropsychopharmacol Biol Psychiatry, 2010 Apr 16. PMID 20138949.
Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. David SP, et al. Nicotine Tob Res, 2010 Mar. PMID 20133381.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.