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AP-2 gamma AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1068a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AP-2 gamma Antibody - Product info | |
| Other Accession | NP_003213 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
AP-2 gamma Antibody - Additional info | |
| Other Names TFAP2C; ERF1; TFAP2G; hAP-2g; AP2-GAMMA; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); estrogen receptor factor 1; transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AP-2 gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
AP-2 gamma Antibody - Application data
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AF1068a (2.5 µg/ml) staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
AP-2 gamma Antibody - Related products
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BACKGROUND
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
REFERENCES
AP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene. Williams CM, et al. EMBO J, 2009 Nov 18. PMID 19798054. Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells. Ailan H, et al. BMC Cancer, 2009 Aug 11. PMID 19671168. Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. Woodfield GW, et al. Clin Cancer Res, 2009 Jun 1. PMID 19458056. Activator protein-2 impairs the invasion of a human extravillous trophoblast cell line. Kotani T, et al. Endocrinology, 2009 Sep. PMID 19443578. Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer. Guler G, et al. Cancer, 2009 Feb 15. PMID 19130459.
