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Goat Anti-APOA5 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-APOA5 Antibody AF1075a
    AF1075a (0.3 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6Q788
Other Accession NP_443200, 116519
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 41213 Da
Additional Information
Gene ID 116519
Other Names Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5, Regeneration-associated protein 3, APOA5, RAP3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-APOA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOA5
Synonyms RAP3
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Cellular Location Secreted.
Tissue Location Liver and plasma.
Research Areas
Citations (0)

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The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.


Interactions between the APOA5 -1131T>C and the FEN1 10154G>T polymorphisms on {omega}6 polyunsaturated fatty acids in serum phospholipids and coronary artery disease. Park JY, et al. J Lipid Res, 2010 Aug 27. PMID 20802161.
Association of apolipoprotein A5 gene polymorphisms and serum lipid levels. Li YY, et al. Nutr Metab Cardiovasc Dis, 2010 Aug 12. PMID 20708914.
Association of the apolipoprotein A5 gene -1131 T>C polymorphism with fasting blood lipids: a meta-analysis in 37859 subjects. Zhao T, et al. BMC Med Genet, 2010 Aug 10. PMID 20696075.
The apolipoprotein A5 (APOA5) gene predisposes Caucasian children to elevated triglycerides and vitamin E (Four Provinces Study). Guardiola M, et al. Atherosclerosis, 2010 Jul 15. PMID 20688329.
Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Hu M, et al. Pharmacogenet Genomics, 2010 Oct. PMID 20679960.

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$ 325.00
Cat# AF1075a
(40 western blots)
Availability: 7-10 days
Bulk Size
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